1801006158 prefinal A 45 year old female with generalised weakness and pedal edema

 This is an online E log book to discuss our patient's de-identified health data shared after taking his/her/guardian's signed informed consent. Here we discuss our individual patient's problems through series of inputs from available global online community of experts with an aim to solve those patient's clinical problems with collective current best evidence based inputs. This E log book also reflects my patient-centred online learning portfolio and your valuable comments on comment box is welcome. I've been given this case to solve in an attempt to understand the topic of "patient clinical data analysis" to develop my competency in reading and comprehending clinical data including history, clinical findings, investigations and come up with a diagnosis and treatment plan

Shivang sharma
2018 batch 

Case report - 
A 45 year old female ,resident of narkatpally came with the chief complaints of 

-- generalised weakness since 15 days 
B/l pedal edema since 15 days 

HOPI -- 

Patient was apparently asymptomatic 15 days back then she developed swelling in both lower limbs which was insidious in onset gradually progressive and pitting type , relieved in night (on rest )
It was previously on and off type bt since 2 to3 days it was not relieving on rest also for which she visited hospital and her hemoglobin level was 4.5 gm / dl , later she had blood transfusion,the pedal edema is relieved
She also complains generalised weakness

No h/o of sob , orthopnea,pnd , palpitation, decreased urine out put , and burning micturition
No h/o abdominal distension,pain , itching,erythema 
No h/o fever ,vomiting, loose stools, constipation

 


Past history -


She had similar complaint of generalised weakness 4years back.

K/c/o diabetes since 3days

Not a k/c/o HTN,Asthma, epilepsy , thyroid disorders,TB, CAD

Menstrual history -


Menarche-At the age of 13years

She had regular periods of 5/28 

She used 2-3pads/day before but since 3months she has increased blood flow on her 1st day of menses for which she used around 4pads/day(fully soaked).

Marital history -


She got married at the age of 15years

1st child- normal vaginal delivery but died after 3days.

2nd child- normal vaginal delivery but died at the age of 6.

3rd,4th and 5th child through normal vaginal delivery and their current age 23yrs,18yrs and 16yrs.

Personal history -

Diet - mixed 
Appetite - decreased
Sleep - adequate
Bowl and bladder movement - regular
No addiction 
No allergy 

Daily routine - 

She used to wake up at 7 am nd do household works , had breakfast at 8 am ,lunch by 2 pm ,dinner by 10 pm and sleep 12 pm , she works in her genral store with her son  
Since few months she used to skip meal 

Family history - not significant 

General examination--

Patient is conscious, coherent and cooperative
Moderately built nd nourished 

Pallor - present 






Icterus - absent




Cyanosis - absent
Clubbing - absent
Generalised lymphadenopathy - absent 
Edema - previously present now resolved








Vitals - 
Temp -96.8° F 
Blood pressure - 110/70 mmHg 
Pulse rate - 89bpm
Respiratory rate - 16 cpm 


Systemic examination -- 

RESPIRATORY examination --


Shape of chest is elliptical
B/L symmetrical
Trachea is central 
Expansion of chest symetrical
Bilateral airway entery 
Normal vesicular breath sound 
No scars ,dilated vein seen 

Per abdomen - 

Inspection - 
Shape - scaphoid
Umbilicus - inverted 
Equal symmetrical movement in all the quadrant with respiration
No visible pulsation , peristalsis ,dilated veins 
No distension

Palpation - 
No local rise of temp 
Inspectory findings are confirmed
No hepatomegaly
Spleen not palpable

Percussion - 
Liver span - 7 cm 
Shifting dullness - absent 
Puddle sign - absent 

Auscultation - bowl sound heard - 6 sound / minute 

Cvs --

Inspection:

There are no chest wall abnormalities 

The position of the trachea is central. 

Apical impulse is not observed. 

There are no other visible pulsations, dilated and engorged veins, surgical scars or sinuses. 


Palpation:

Apex beat was localised in the 5th intercostal space 1cm medial to the mid clavicular line 

Position of trachea was central 

There we no parasternal heave , thrills, tender points. 


Auscultation: 

Loud S1 and S2

There were no added sounds / murmurs. 

CNS -


HIGHER MENTAL FUNCTIONS- 

Normal

Memory intact

CRANIAL NERVES :Normal

SENSORY EXAMINATION

Normal sensations felt in all dermatomes

MOTOR EXAMINATION

Normal tone in upper and lower limb

Normal power in upper and lower limb

Normal gait

REFLEXES

Normal, brisk reflexes elicited- biceps, triceps, knee and ankle reflexes elicited

Reflexes video --





CEREBELLAR FUNCTION-

Normal function

No meningeal signs were elicited

Provisional diagnosis -

This is case of 45 year old female having anemia secondary to ?heavy menstrual bleeding


INVESTIGATIONS:

On 7/6/23: 










ECG - 


USG -


Evidence of few calculi 3-4mm noted in the lower pole of right kidney 


Evidence of 5.8x4.8 cm fibroid in the posterior myometrium


Impression:

Borderline spleenomegaly 

Right renal calculi 

Posterior myometrial fibroid 


13 June 2023--

Hb- 5gm/dl 

TLC - 5800 

MCV - 61.7 

MCHC - 23.1

MCH - 14.3 

Platelet - 3.0  

Serum iron - 31 micro gram / dl 

Blood urea - 22 mg/dl 

Serum creatinine - 0.6 mg/ dl 

Blood grouping - B +ve 

Serum ferritin - 2.2ng/ml

Liver function test --


14 June 2023 

Fasting Blood sugar -285 mg/dl  


Chest x-ray:





15/06/23 


2D eco --






Final diagnosis:

This is case of 45 year old female having 

Anemia-nutritional(iron deficiency anemia)secondary to ?heavy menstrual bleeding
Denovo DM 2 
Right renal calculi

OBG Referral on 13/6/23:

O/E:

45year old P5L3D2 tubectomised with AUB-L with severe anemia 

Patient not willing for per speculum and bimanual examination 

Advice : 

No active gynaecological intervention needed 


Blood transfusion of 1unit PRBC was done on 13/6/23


Treatment:-


INJ.IRON SUCROSE 200MG IN 100ML NS IV/OD OVER 1 HOUR.

INJ.OPTINEURON 1 AMP IN 100 ML NS IV/OD 

TAB.METFORMIN 500MG PO/BD

TAB.GLIMIPIRIDE 1MG PO/OD


Why does edema develop in chronicle anemia ??

. It is suggested that the low concentration of haemoglobin in patients with anaemia causes a reduced inhibition of basal endothelium-derived relaxing factor activity and leads to generalised vasodilatation. The consequent low blood pressure may be the stimulus for neurohormonal activation and salt and water retention.






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